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Is Pro-Stride right for your horse?

March 28, 2018

Peninsula Equine Medical Center is always proud to offer the latest in regenerative medicine, including Pro-Stride Advanced Joint Therapy. We have been using Pro-Stride in our patients for over one-and-a-half years, and are extremely happy with the success our patients have had. It was added to our extensive arsenal of modalities which include other regenerative medicine procedures such as IRAP, PRP, and stem cells therapy.

Pro-Stride is an Autologous Protein Solution (APS) containing a high concentration of cells, platelets, growth factors, and anti-inflammatory proteins to treat inflammatory processes in joints. This all-natural, drug-free option takes 20 minutes to process with no incubation time and treatment can be provided in a single visit. Additional benefits to Pro-Stride including as no withholding time for both FEI and USEF events.


Following a single injection, Pro-Stride APS has clinically demonstrated pain relief in horses at 52-weeks.



In degenerative joint diseases, such as arthritis, inflammatory cells bind to the cell receptors on the joint surface and starts breaking down the cartilage. Cartilage breakdown leads to joint damage and pain. Interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF-alpha) are two major pro-inflammatory proteins, also known as cytokines, which lead to the degeneration of the joints.


Pro-Stride works by blocking these pro-inflammatory cytokines from binding to the cartilage surface. APS is concentrated plasma with white blood cell proteins and enriched platelet growth factors derived from the horse’s own blood. Specifically, Pro-Stride APS is a high concentration of interleukin-1 receptor antagonist (IRAP) that is 5.8 times more concentrated than blood. These receptor antagonists promote natural joint healing processes.



The Pro-Stride processing unit is mobile and the entire process takes about 30-minutes. Blood is drawn from the horse then placed in a centrifuge to be spun down. Then plasma is removed and the remaining PRP suspension is extracted. This extraction is then added to an APS concentration device which undergoes mixing, then is spun down once more. The resulting product is Autologous Protein Solution (APS). This can then be injected into the joint by your veterinarian all at the same appointment.


Talk to us today to see if Pro-Stride is the best treatment choice for your horse!


To see publications showing clinical data supporting the effects of Pro-Stride APS, please visit:



Here is a YouTube video showing how Pro-Stride works:




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